The analysis of three-dimensional (3D) structure is of great importance for the mechanism of virus infection and the design of antiviral drugs. Although many breakthroughs have been made in structural biology techniques and structure determination methods such as X-ray crystallography, NMR spectroscopy and cryo-electron microscopy (cryo-EM) have been utilized to determine the structure of many biological macromolecules, the process of obtaining the 3D structure of the target protein is still difficult and time-consuming. SARS-CoV-2 protein homology modeling https://www.creative-biostructure.com/coronavirus/protein-homology-modeling-for-coronavirus-research-p18.htm
