Bile acids formed by synthesis in the liver are termed primary bile acids. In the liver, synthesis of bile acids and bile salts is initiated with the conversion of cholesterol esters to cholesterol. The primary bile acids are conjugated with taurine or the amino acid glycine before secretion via bile into the intestine, where they function as detergents to solubilize dietary fats. Conjugation increases water solubility, preventing passive re-absorption once secreted into the small intestine. bile acids analysis tissues https://metabolomics.creative-proteomics.com/primary-bile-acid-biosynthesis-analysis-service.htm